Compounded Tirzepatide Dosage Calculator

Calculate appropriate compounded tirzepatide dosages, titration schedules, and treatment requirements based on patient-specific factors and clinical guidelines.

Patient Weight Enter patient weight in kilograms (kg)

Starting Dose Initial tirzepatide dose in milligrams (mg)

Target Dose Maximum planned tirzepatide dose in milligrams (mg)

Current Dose Patient's current tirzepatide dose in milligrams (mg)

Medication Concentration Concentration of compounded tirzepatide in mg/mL

Titration Interval Weeks between dose increases

Treatment Duration Total planned treatment duration in weeks

Unit Preference

Quick Examples:

How to Use This Calculator

Enter the patient's weight in kilograms
Specify the starting, current, and target tirzepatide doses
Input the concentration of the compounded medication
Set the titration interval and treatment duration
Click Calculate to view the dosage schedule and treatment plan

Formula Used

Volume (mL) = Dose (mg) ÷ Concentration (mg/mL)

Where:

Volume = Amount of medication to administer
Dose = Prescribed tirzepatide amount
Concentration = Strength of compounded medication

Example Calculation

Real-World Scenario:

A patient weighing 85 kg is starting tirzepatide for weight management. The compounded medication has a concentration of 5 mg/mL, with a starting dose of 2.5 mg and target dose of 15 mg.

Given:

Patient Weight = 85 kg
Starting Dose = 2.5 mg
Target Dose = 15 mg
Concentration = 5 mg/mL

Calculation:

Starting Volume = 2.5 mg ÷ 5 mg/mL = 0.5 mL

Target Volume = 15 mg ÷ 5 mg/mL = 3.0 mL

Result: The patient will start with 0.5 mL weekly and titrate up to 3.0 mL weekly over approximately 28 weeks.

Why This Calculation Matters

Practical Applications

Ensures accurate dosing for compounded medications
Helps plan medication supply for treatment duration
Provides clear titration schedule for patients

Key Benefits

Reduces dosing errors with compounded medications
Optimizes treatment outcomes with proper titration
Helps estimate medication costs and supply needs

Common Mistakes & Tips

Always verify the concentration of your compounded tirzepatide, as different pharmacies may compound it at different strengths. Using the wrong concentration will result in incorrect dosing calculations.

Increasing tirzepatide doses too quickly can lead to significant gastrointestinal side effects. The recommended titration interval is at least 4 weeks between dose increases to allow for tolerance development.

Frequently Asked Questions

The typical starting dose for tirzepatide is 2.5 mg once weekly, regardless of whether it's being used for type 2 diabetes or weight management. This lower starting dose helps minimize gastrointestinal side effects.

The dose should be increased no more frequently than every 4 weeks. The typical titration schedule is 2.5 mg → 5 mg → 7.5 mg → 10 mg → 12.5 mg → 15 mg, with at least 4 weeks at each dose level.

When properly compounded by a reputable pharmacy using quality ingredients, compounded tirzepatide should have the same efficacy as brand-name versions. However, quality can vary between compounding pharmacies, so it's important to use a trusted provider.

References & Disclaimer

Medical Disclaimer

This calculator is for informational purposes only and does not constitute medical advice. Always consult with a healthcare provider before starting or adjusting any medication. The dosage calculations provided should be verified by a qualified medical professional.

References

Tirzepatide Once Weekly for the Treatment of Obesity - SURMOUNT-1 Trial Results
Tirzepatide for Type 2 Diabetes - SURPASS Program Clinical Trials
FDA Warning on Compounded GLP-1 Medications - FDA Safety Communication

Accuracy Notice

This calculator provides estimates based on standard dosing protocols. Individual patient needs may vary based on medical history, concurrent medications, and response to treatment. The calculations should be used as a starting point for clinical decision-making, not as a substitute for professional medical judgment.

About the Author

Kumaravel Madhavan

Web developer and data researcher creating accurate, easy-to-use calculators across health, finance, education, and construction and more. Works with subject-matter experts to ensure formulas meet trusted standards like WHO, NIH, and ISO.

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health medical-clinical-calculators compounded tirzepatide dosage medical body weight

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